Serum Samples That Have Been Stored Long-Term (>10 Years) Can Be Used as a Suitable Data Source for Developing Cardiovascular Risk Prediction Models in Large Observational Rheumatoid Arthritis Cohorts

Table 3

Effect of storage time (years) on HDL-c levels, adjusted results.

	Estimate	SE	value	95% CI
				Lower	Upper
Constant	1.247	0.056	<0.0001	1.136	1.358
Storage time	−0.024	0.002	<0.0001	−0.027	−0.021
Time within patients (follow-up)	0.003	0.001	<0.0001	0.001	0.004
Time within patients^2 (follow-up)	−0.00003	0.00001	<0.0001	−0.00004	−0.00002
Age	0.003	0.001	0.001	0.001	0.004
Gender	−0.074	0.021	0.001	−0.117	−0.031

(i) SE, standard error; 95% CI, 95% confidence interval.
(ii) Data are adjusted for age, gender, and time within patients².