The (G>A) rs11573191 Polymorphism of PLA2G5 Gene Is Associated with Premature Coronary Artery Disease in the Mexican Mestizo Population: The Genetics of Atherosclerotic Disease Mexican Study
Table 1
Demographic characteristics of the studied population.
Controls
Premature CAD
( = 749)
( = 707)
Age (years)
53.99 ± 9.82
53.3 ± 7.4
0.982
Gender (% male)
49.7
81.4
<0.0001
Body mass index (kg/m2)
28.47 ± 4.44
28.77 ± 4.29
0.184
Obesity (%)
31.5
35.3
0.067
Waist circumference (cm)
94.38 ± 11.62
98.06 ± 11.32
<0.0001
Central obesity (%)
79.7
82
0.144
Total abdominal fat (cm2)
438.44 ± 163.17
424.59 ± 166.62
0.110
Subcutaneous abdominal fat (cm2)
181.30 ± 120.63
248.95 ± 110.14
<0.0001
Visceral abdominal fat (cm2)
157.09 ± 70.70
175.71 ± 81.70
<0.0001
Visceral/subcutaneous adipose tissue ratio
1.99 ± 1.00
1.54 ± 0.81
<0.0001
Current smokers (%)
21.4
12.3
<0.0001
Former smokers (%)
36.8
64.4
<0.0001
Hypertension (%)
24.9
64.9
<0.0001
Hypertensive medication (%)
11.2
89.9
<0.0001
Diastolic blood pressure (mmHg)
74.53 ± 10.09
74.16 ± 10.25
0.497
Systolic blood pressure (mmHg)
121.56 ± 18.83
121.48 ± 19.45
0.942
Heart rate (bpm)
65.54 ± 9.20
64.99 ± 11.00
0.301
Data are expressed as means ± SD; log-transformed values were used for statistical analysis. values were estimated using ANOVA for continuous variables and Pearson’s Chi-square test for categorical values. CAD: coronary artery disease.
