Is Contrast Medium Osmolality a Causal Factor for Contrast-Induced Nephropathy?

Table 1

Meta-analyses for CIN comparison of LOCM* versus IOCM** (mainly I.A.).

Authors (date)	Search results	Analyzed trials	Total patients	Dates included	Agent superiority
Solomon (2005), [10]	1,594	17	1,365	1991–2004	LOCM = IOCM > Iohexol
McCullough et al. (2006), [11]	Iohexol database	16	2,727	1991–2003	IOCM > LOCM
Heinrich et al. (2009), [12]	926	25	3,270	1950–2007	LOCM = IOCM > Iohexol
From et al. (2010), [13]	112 (abstracts)	36	7,166	1966–2009	IOCM ≥ LOCM

∗LOCM: low osmolality contrast media.
∗∗IOCM: iso-osmolar contrast media.