Review Article
Is Contrast Medium Osmolality a Causal Factor for Contrast-Induced Nephropathy?
Table 2
Clinical studies for CIN comparison of LOCM* versus IOCM** (mainly I.V.).
| | Authors (date) | Patients evaluated
(originally included) | CIN
absolut1
(relative2)
LOCM | CIN
absolut1
(relative2)
IOCM | Agent superiority |
| | Barrett et al. (2006), [14] | 153
(166) | 0/77
(3/77) | 2/76
(3/76) | LOCM = IOCM |
| | Kuhn et al. (2008), [15] | 248
(264) |
(6/123) |
(7/125) | LOCM = IOCM |
| | Thomsen et al. (2008), [16] | 148
(184) | 0/76
(4/76) | 5/72
(5/72) | LOCM > IOCM |
| | Nguyen et al. (2008), [17] | 126
(117) | 10/56
(15/56) | 3/61
(5/61) | IOCM > LOCM |
|
|
LOCM: low osmolality contrast media.
**IOCM: iso-osmolar contrast media.
SCr: serum creatinine.
CIN: contrast-medium induced nephropathy.
1SCr increase ≥0.5 mg/dL.
2SCr increase ≥25%.
|
