Research Article

The Biological Effects of Sex Hormones on Rabbit Articular Chondrocytes from Different Genders

Table 1

The expression of collagen I and collagen II on different groups with analysis by RT-PCR.

Sex hormoneExpression of collagen I (X-fold of control)Expression of collagen II (X-fold of control)
MaleFemaleMaleFemale

Estradiol
 10−6 ( )0.77 (0.65 to 0.89)0.52 *(0.41 to 0.64)1.48 (1.39 to 1.56)1.89 *(1.76 to 2.02)
 10−7 ( )0.89 (0.68 to 1.14)0.56 *(0.47 to 0.65)1.52 (1.39 to 1.65)1.96 *(1.72 to 2.21)
Testosterone
 10−6 ( )0.98 (0.87 to 1.09)0.89 (0.78 to 1.01)1.24 (0.77 to 1.71) 1.31 (1.09 to 1.53)
 10−7 ( )0.89 (0.68 to 1.10)0.78 (0.66 to 0.91)1.21 (0.74 to 1.68)1.28 (1.05 to 1.51)

Values are the mean (95% confidence interval [CI]).
: number of chondrocytes samples.
by multiway ANOVA.