Isocudraxanthone K Induces Growth Inhibition and Apoptosis in Oral Cancer Cells via Hypoxia Inducible Factor-1α
Figure 4
Effects of isocudraxanthone K (IK) on expression of apoptosis regulatory proteins in HN4 (a) and HN12 (b) cells. Cells were cultured with the indicated dose of IK for 2 days. The histogram shows the quantification of mRNA or protein expression by densitometry and is presented as fold increases compared to nonstimulated control cells. The results are representative of three independent experiments. Statistically significant difference, compared with control, .
