The Role of Genetic Factors and Kidney and Liver Function in Glycemic Control in Type 2 Diabetes Patients on Long-Term Metformin and Sulphonylurea Cotreatment

Table 2

SLC22A1 in SLC47A1 genotype frequencies and the risk for hypoglycemia events.

Polymorphism	Genotype	All patients		Patients with hypoglycemia
		𝑁 (%)	MAF	𝑁 (%)	𝑃	OR (95% CI)
SLC47A1; rs2289669	GG	54 (40.3)	0.355*	10 (18.5)	0.310	1.38; (0.74–2.59)
	GA	65 (48.5)		13 (20.0)
	AA	15 (11.2)		5 (33.3)
SLC22A1; rs628031	GG	51 (37.8)	0.385	15 (29.4)	0.046	0.51 (0.26–0.99)
	GA	64 (47.4)		11 (17.2)
	AA	20 (14.8)		2 (10.0)

∗Data missing for 1 patient; MAF: minor allele frequency.