Structural Basis of Binding and Rationale for the Potent Urease Inhibitory Activity of Biscoumarins

Figure 7

A view showing the interaction of compound 2 (yellow) with urease (Bacillus pasteurii). Ligand 2 is unable to reach the nickel (green) metalocentre and bind outside the active site. Helix (Red), sheet (yellow), and loop (green).