Renal Overexpression of Atrial Natriuretic Peptide and Hypoxia Inducible Factor-1 as Adaptive Response to a High Salt Diet

Table 1

Renal function parameters.

	NS	HS	NS-T	HS-T
PLNa (mEq·L^−1)	142±1	145±2	143±1	143±2
GFR (mL·min^−1)	1.51±0.1	1.48±0.1	3.4±0.8^†	3.1±0.7^†
UVNa (μmol·min^−1·kg^−1)	0.23±0.1	3.50±0.64^∗	2.00±0.92^†	13.0±1.5^∗†
FENa (%)	0.04±0.02	0.53±0.08^∗	0.12±0.06	1.20±0.20^∗†

All values are mean ± SEM, 𝑛=5-6, *𝑃<0.05 versus respective NS group, ^†𝑃<0.05 versus respective group without tempol. NS: normal salt diet group, HS: high salt diet group, NS-T: normal salt diet plus tempol group, HS-T: high salt diet plus tempol group, PL_Na: plasmatic sodium concentration, GFR: glomerular filtration rate, UV_Na: urinary sodium excretion, and FE_Na: fractional sodium excretion.