Directly-Observed Intermittent Therapy versus Unsupervised Daily Regimen during the Intensive Phase of Antituberculosis Therapy in HIV Infected Patients

Table 1

Baseline characteristics and balance before and after inverse probability weighting based on propensity scores of 1460 HIV infected patients with tuberculosis in Anantapur, India.

	Baseline characteristics		Unweighted means			Weighted means
	I-ATT (𝑛=343); 𝑁 (%)	D-ATT (𝑛=1117); 𝑁 (%)	I-ATT	D-ATT	Standardized; difference	I-ATT	D-ATT	Standardized; difference
Female	125 (36.4)	387 (34.6)	36.40%	34.60%	0.038	34.50%	34.90%	0.009
Homeless	16 (4.7)	28 (2.5)	4.70%	2.50%	0.126	3.20%	2.70%	0.028
Illiteracy	199 (58)	605 (54.2)	58.00%	54.20%	0.077	57.10%	54.70%	0.048
Sputum smear+	104 (30.3)	291 (26.1)	30.30%	26.10%	0.096	28.40%	26.70%	0.039
Disadvantaged community	104 (30.3)	353 (31.6)	30.30%	31.60%	0.028	31.70%	31.50%	0.004
Previous ATT	57 (16.6)	161 (14.4)	16.60%	14.40%	0.062	15.10%	14.70%	0.011
Disseminated TB	15 (4.4)	55 (4.9)	4.40%	4.90%	0.026	4.30%	4.90%	0.029
On ART	146 (42.6)	392 (35.1)	42.60%	35.10%	0.155	38.30%	36.10%	0.045
Age (years)	35 (28.7–40)*	35.4 (30–42.2)*	34.626	36.712	0.204	35.614	36.263	0.065
CD4 count (cells/mm^3)	120.5 (68–204)*	124 (63–228)*	182.884	170.705	0.067	168.382	173.853	0.029
CD4 count unknown	25 (7.3)	63 (5.6)	7.30%	5.60%	0.063	5.50%	5.80%	0.013
Serum albumin (g/dL)	3 (2.5–3.5)*	3 (2.5–3.5)*	3.034	2.968	0.089	2.977	2.976	0.001

∗Median (interquartile range). ART, antiretroviral therapy; I-ATT, intermittent anti-tuberculosis therapy; D-ATT, daily anti-tuberculosis therapy; TB, tuberculosis.