Montanoa frutescens and Montanoa grandiflora Extracts Reduce Anxiety-Like Behavior during the Metestrus-Diestrus Phase of the Ovarian Cycle in Wistar Rats
Table 1
Variables evaluated in the elevated plus maze without significant changes associated with treatment and phase of the ovarian cycle.
Group
Number of entries into the open arms
Total number of entries into the arms (open + close)
P-E
M-D
P-E
M-D
Vehicle
10.11 ± 1.86
5.63 ± 2.07
13.22 ± 2.08
14.50 ± 2.06
Mf (mg/kg)
25
7.75 ± 1.71
6.50 ± 0.95
13.87 ± 3.56
10.25 ± 2.39
50
7.11 ± 0.91
8.00 ± 1.11
9.56 ± 1.60
10.87 ± 1.79
Mg (mg/kg)
25
5.66 ± 0.67
7.67 ± 0.85
8.44 ± 0.61
9.67 ± 0.57
50
7.11 ± 1.21
7.10 ± 0.96
10.11 ± 0.77
9.50 ± 0.83
Diazepam (mg/kg)
2
8.78 ± 0.82
8.13 ± 0.97
11.22 ± 1.21
11.25 ± 1.49
No significant differences among subgroups were found, two-way ANOVA. Mf: M. frutescens; Mg: M. grandiflora; P-E: proestrus-estrus phase; M-D: metestrus-diestrus phase.
