Pleurodesis Induction in Rats by Copaiba (Copaifera multijuga Hayne) Oil

Table 2

Distribution according to the mean of the scores of the variables analyzed.

Variable	24 h	48 h	72 h	504 h
	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD
Parietal fibrosis
Copaiba oil	—	—	0.63 ± 0.52	0.50 ± 0.78
Silver nitrate	—	—	0.38 ± 0.52	0.75 ± 0.71
𝑃^∗	—	—	0.350	0.506
Visceral fibrosis
Copaiba oil	—	—	0.00 ± 0.00	1.38 ± 0.74
Silver nitrate	—	—	0.25 ± 0.71	0.50 ± 0.54
𝑃^∗	—	—	—	0.017
Parietal neovascularization
Copaiba oil	—	0.25 ± 0.46	0.63 ± 0.52	0.50 ± 0.53
Silver nitrate	—	0.50 ± 0.53	0.63 ± 0.52	0.63 ± 0.74
𝑃^∗	—	0.334	0.999	0.705
Visceral neovascularization
Copaiba oil	0.00 ± 0.00	—	0.25 ± 0.46	1.50 ± 1.07
Silver nitrate	0.13 ± 0.35	—	0.62 ± 0.92	0.34 ± 0.52
𝑃^∗	0.334	—	0.319	0.018
Parietal edema
Copaiba oil	0.50 ± 0.53	0.75 ± 0.46	1.25 ± 0.71	0.63 ± 0.74
Silver nitrate	0.38 ± 0.52	0.88 ± 0.35	1.00 ± 0.53	0.63 ± 0.74
𝑃^∗	0.642	0.554	0.438	0.999
Visceral edema
Copaiba oil	0.38 ± 0.52	0.87 ± 0.64	1.62 ± 0.92	1.50 ± 0.76
Silver nitrate	0.88 ± 0.35	1.25 ± 0.46	1.38 ± 0.52	1.38 ± 0.52
𝑃^∗	0.041	0.201	0.513	0.705
Fibroblastic proliferation
Parietal pleura
Copaiba oil	—	0.50 ± 0.76	0.62 ± 0.52	0.75 ± 1.03
Silver nitrate	—	0.63 ± 0.52	1.25 ± 0.46	0.63 ± 0.52
𝑃^∗	—	0.705	0.023	0.764
Fibroblastic proliferation
Visceral pleura
Copaiba oil	—	0.13 ± 0.35	1.12 ± 0.64	1.12 ± 0.83
Silver nitrate	—	0.25 ± 0.46	0.75 ± 0.89	0.75 ± 0.46
𝑃^∗	—	0.554	0.349	0.285
Alveolar edema
Copaiba oil	0.00 ± 0.00	0.25 ± 0.71	0.00 ± 0.00	—
Silver nitrate	1.50 ± 1.20	0.50 ± 0.53	0.50 ± 0.76	—
𝑃^∗	0.003	0.438	0.082	—

∗Student’s 𝑡-test. Value of 𝑃 in bold italic indicates statistical difference at 5%.