BioMed Research International / 2014 / Article / Tab 5

Research Article

Prevalence of Past and Reactivated Viral Infections and Efficacy of Cyclosporine A as Monotherapy or in Combination in Patients with Psoriatic Arthritis—Synergy Study: A Longitudinal Observational Study

Table 5

List of adverse events.

Adverse eventSeverityDrug-related Systemic treatment of psoriasis or psoriatic arthritis concomitant to adverse event

Increased creatinine and increased serum cholesterol MildYes, cyclosporineCyclosporine
Increased creatinineMildYes, cyclosporineCyclosporine, sulfasalazine
Gingival hyperplasia and gingival bleedingMildYes, cyclosporineNone
TremorMildYes, cyclosporineCyclosporine
Burning urinationMildNoCyclosporine, methotrexate, quinolones
Urethritis MildNoFans
Urethritis (Proteus mirabilis)MildNoFans
HypertensionModerateYes, cyclosporineEtanercept, cyclosporine
Increased creatinineModerateYes, cyclosporineCyclosporine
Fatigue, stomatitis, gastrointestinal disorders, and vomitingModerateYes, cyclosporineCyclosporine
Nausea and vomitingModerateYes, cyclosporineCyclosporine, methotrexate
Hypertension, altered liver Function testsModerateYes, cyclosporineCyclosporine
Fever, sore throat, hyposmia, hypoacusiaModerateNoMethotrexate
Postmicturition syncopeModerateNoCyclosporine
Presyncopal episode preceded by autonomic problems (sweating, dizziness, nausea) after several episodes of diarrhea (enteritis) ModerateNoCyclosporine
Renal colicModerateNoCyclosporine, leflunomide
Syncopal episodeSeriousUKNCyclosporine, methotrexate
Outcomes of central vein occlusionUKNYes, infliximabInfliximab, methotrexate, cyclosporine