Research Article

Beta-Catenin and Epithelial Tumors: A Study Based on 374 Oropharyngeal Cancers

Table 1

Clinicopathological characteristic of study population.

Age
 Range 33–98
 Mean 65,34
Sex
 Male 289
 Female 85
Ethnic group
 Caucasian White286
 American White61
 Hispanic19
 American Black8
Site
 Trigonous (Tr)14
 Tongue (T)168
 Gums (G)18
 Cheek (C)*34
 Lip (L)29
 Bone Involvement (BI)**23
 Oropharynx (OP)4
 Palate (P)12
 Floor of the mouth (FOM)46
 Multiple sites (MS)***11
 Metastasis (Met)****15
 Total374
Maximum diameter (cm)
 <2 cm102
 >2 cm272

TNM staging

 TN0 M0N0 M1N1 M0N1 M1Total

 T1863253117
 T2720577136
 T313029850
 T425139671
 Total196415024374

Stage
 St186
 St272
 St3124
 St492
Histologic grade
 G162
 G2188
 G3124
Follow-up
 Alive142
 Dead for disease207
 Dead for other causes25
Local recurrence
 No 215
 Yes 159
Therapy
 CH233
 CH-RT/CH-RT-CHT59
 RT82

Legend: *Cheek includes gingival mucosa.
**Bone involvement of mandible or upper alveolar process.
***Multiple sites includes FM + Tr, T + Tr, T + G, C + L, T + C, T + L.
****Metastases analyzed without primary tumors due to not operable advanced stages primary cancer.