Exploring the miRNA-mRNA Regulatory Network in Clear Cell Renal Cell Carcinomas by Next-Generation Sequencing Expression Profiles
Figure 2
Potential of miRNAs to distinguish between normal and ccRCC tissue samples. (a) PCA of normalized expression values of miRNAs differentially expressed between conditions. The first principal component is given on the -axis and the second on the -axis. (b) value distribution of all miRNAs. (c) Unsupervised hierarchical cluster analysis of differentially expressed miRNAs. (d) An MA plot that visualizes the relation between log2 fold change between controls and cancer patients and the log2 average gene expression. MiRNAs with an FDR adjusted value < 0.1 are indicated in red.
