Evaluation of Buspirone on Streptozotocin Induced Type 1 Diabetes and Its Associated Complications

Table 2

Effect of buspirone on lipid parameters.

Lipid parameters	CON	COB	DIC	DIB
Serum triglyceride (mg/dL)	43.03±3.51	43.72±5.83	193.85±14.47^∗	134.73±3.03
Total serum cholesterol (mg/dL)	71.32±3.00	73.07±4.85	93.63±2.40^∗	83.57±3.11
Serum VLDL-C (mg/dL)	8.89±0.67	8.74±1.17	38.77±2.89^∗	26.95±0.61
Serum LDL-C (mg/dL)	24.69±1.36	26.79±3.79	38.45±1.92^∗	29.53±0.83
Serum HDL-C (mg/dL)	29.79±3.07	27.02±2.00	13.21±1.26^∗	18.62±2.33
Log TG/HDL ratio	0.0069±0.0006	0.0084±0.0008	0.02806±0.0023	0.0188±0.0014

∗Significantly different from normal control (𝑃<0.05).
^#Significantly different from diabetic control (𝑃<0.05).
Values are expressed as mean ± SEM of 6 experiments.
CON: normal control, COB: control treated with buspirone, DIC: diabetic control, and DIB: diabetic treated with buspirone.