Research Article

Endometrial Receptivity Profile in Patients with Premature Progesterone Elevation on the Day of hCG Administration

Figure 2

Signalling pathways that were altered in the high serum [P] group. The Ingenuity Pathway software was used to identify the functional pathways associated with genes that were differentially expressed between the prereceptive and receptive endometrial stages in the high [P] group. The majority of genes related to mitotic entry (a) and cell cycle (b) were downregulated. In this network, edge types are indicatives: a plain line indicates direct interactions, a dashed line indicates indirect interactions, a line without arrowhead indicates binding only, a line finishing with a vertical line indicates inhibition, and a line with an arrowhead indicates “acts on”. Green, downregulated; red, upregulated.
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(a) Mitotic entry
951937.fig.002b
(b) Network around the cell cycle