Molecular Mechanisms for Biliary Phospholipid and Drug Efflux Mediated by ABCB4 and Bile Salts

Figure 2

Amino acid sequence alignment of human ABCB1 and ABCB4. Identical amino acids are red. Functional domains are shown above the sequence alignment. TMHs are predicted from the crystal structure of mouse Abcb1a (PDB code 3G61) reported by Aller et al. [60].