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BioMed Research International
Volume 2014, Article ID 956952, 7 pages
http://dx.doi.org/10.1155/2014/956952
Research Article

Biodegradable and Elastomeric Poly(glycerol sebacate) as a Coating Material for Nitinol Bare Stent

1Department of Polymer Science and Engineering, Sungkyunkwan University, Suwon 440746, Republic of Korea
2School of Chemical Engineering, Sungkyunkwan University, Suwon 440746, Republic of Korea

Received 10 January 2014; Revised 4 March 2014; Accepted 2 April 2014; Published 13 May 2014

Academic Editor: Yoshihiro Ito

Copyright © 2014 Min Ji Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We synthesized and evaluated biodegradable and elastomeric polyesters (poly(glycerol sebacate) (PGS)) using polycondensation between glycerol and sebacic acid to form a cross-linked network structure without using exogenous catalysts. Synthesized materials possess good mechanical properties, elasticity, and surface erosion biodegradation behavior. The tensile strength of the PGS was as high as 0.28 ± 0.004 MPa, and Young's modulus was 0.122 ± 0.0003 MPa. Elongation was as high as 237.8 ± 0.64%, and repeated elongation behavior was also observed to at least three times the original length without rupture. The water-in-air contact angles of the PGS surfaces were about 60°. We also analyzed the properties of an electrospray coating of biodegradable PGS on a nitinol stent for the purpose of enhancing long-term patency for the therapeutic treatment of varicose veins disease. The surface morphology and thickness of coating layer could be controlled by adjusting the electrospraying conditions and solution parameters.