Research Article

In Silico Molecular Docking and In Vitro Antidiabetic Studies of Dihydropyrimido[4,5-a]acridin-2-amines

Table 1

Summary of synthesized 2-aminopyrimidine derivatives (3a–f) via Scheme 1.

S. no.CompoundsRM.P. (°C)Yield%

13a-H194–19670
23b-3,4-OCH3218–22081
33c-2,5-OCH3212–21475
43d-2-OCH3168–17069
53e-4-Cl210–21271
63f-2-Cl238–24069