CB2 Receptor Activation Ameliorates the Proinflammatory Activity in Acute Lung Injury Induced by Paraquat

Figure 1

Effects of JWH133 on lung W/D ratio and histopathological changes in lung tissues of PQ-induced acute lung injury rats. JWH133 was intraperitoneally administered 1 h before intraperitoneal administration of PQ. The lung W/D ratio (a, b) and lung histological evaluation (c, d, HE staining) were determined after PQ administration for 72 h. L-JWH133: JWH133 at the low dose of 5 mg/kg and H-JWH133: JWH133 at the high dose of 20 mg/kg. The values presented are the mean±SD. ^∗𝑃<0.05 versus PQ group; ^#𝑃<0.05 versus L-JWH133 group.

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