Computational Biophysical, Biochemical, and Evolutionary Signature of Human R-Spondin Family Proteins, the Member of Canonical Wnt/β-Catenin Signaling Pathway
Figure 11
Phylogenetic analysis using different human (Rspo)s which shows the relationship between the family members. (a) A phylogenetic tree showing the evolution in the relationships between human (Rspo)s. Bootstrap values are pointed out at nodes. R-spondins protein family members names at the clade, (b) cladogram of protein sequences of the (Rspo)s members, (c) binary tree representation equivalent to cladogram, (d) phylogenetic tree (alpha circular type) reconstructed using the maximum likelihood method. The symbol adjacent to the node indicates the origin point of the proteins, (e) phylogenetic tree developed through clustal-omega server where the value of the branch length is mentioned immediately leading to the node, and (f) comparison between the value of the branch lengths.
