Clinicopathological Factors Affecting Survival and Recurrence after Initial Hepatectomy in Non-B Non-C Hepatocellular Carcinoma Patients with Comparison to Hepatitis B or C Virus

Table 2

Intraoperative, pathological and postoperative factors.

	B (𝑛=32)	C (𝑛=93)	NBNC (𝑛=76)	𝑃 value
≧2 sentionectomy	13 (40.6%)	17 (18.3%)	32 (42.1%)	0.002
Operative Time (min.)	352 (177–658)	333 (135–750)	367 (173–983)	0.142
Blood loss (g)	1137 (38–8488)	1182 (5–8307)	1226 (200–36000)	0.590
Curability R0	27 (84.4%)	88 (94.6%)	70 (92.1%)	0.181
Simple nodular type	12 (37.5%)	54 (58.1%)	30 (39.5%)	0.025
Poorly differentiated	6 (18.8%)	14 (15.1%)	6 (7.9%)	0.218
fc(+)	24 (75.0%)	63 (67.7%)	44 (57.9%)	0.182
vp(+)	17 (53.1%)	24 (25.8%)	28 (36.8%)	0.016
vv(+)	5 (15.6%)	4 (4.3%)	7 (9.2%)	0.109
im(+)	6 (18.8%)	7 (7.5%)	7 (9.2%)	0.181
Non-cancerous liver NL	1 (3.1%)	1 (1.1%)	23 (30.3%)	<0.001
CH	17 (53.1%)	44 (47.3%)	29 (38.2%)	0.288
LC	14 (43.8%)	48 (51.6%)	23 (30.3%)	0.020
Clavien-Dindo ≧ III	5 (15.6%)	19 (20.4%)	12 (15.8%)	0.688
PHLF B/C	7 (21.9%)	28 (30.1%)	18 (23.7%)	0.526
90-day mortality	4 (12.5%)	6 (6.5%)	6 (7.9%)	0.552
Intrahepatic recurrence	13 (40.6%)	47 (50.5%)	25 (32.9%)	0.068
Extrahepatic recurrence	7 (21.9%)	8 (8.6%)	7 (9.2%)	0.096

fc: formation of capsule; vp: microscopic portal vein invasion; vv: microscopic hepatic vein invasion; im: intrahepatic metastasis; NL: normal liver; CH: chronic hepatitis; LC: liver cirrhosis; PHLF: posthepatectomy liver failure.