|
| | Setting | Age (mean) | Ventilatory treatment | ABG pH
PaCO2 (mmHg) P/F | APACHE score (II or III) | Pts with more than 1 comorbidity (%) | Criteria to find comorbidity | Predictors of failure treatment and mortality |
|
Dewan et al.
(Chest 2000) [21] | Outpatients | 66 | No ventilatory treatment | — | — | 87 | Chronic comorbidities | Home oxygen therapy
Rate of exacerbations
Number of comorbidities |
| Connors et al. (AMJRCCM 1996) [22] | Hospital wards and ICUs | 70 | Generically mechanical ventilation (35% of pts) | 7.36
56
211 | (III) 39 | 97 | Acute comorbidities (causes of COPD exacerbation) and number of chronic ones | APACHE score
PaO2/FiO2, ADL, CHF
BMI, cor pulmonale
Causes of COPD exacerbations |
Moretti et al.
(Thorax 2000) [12] | RICUs | 70 | NIMV (100% of pts at admission)
IMV (22% of NIMV failed pts) | 7.23
85
— | (II) 22 | 45 (successful group)
70 (failure group) | Cardiac comorbidities and other complications
(pulmonary, metabolic,
renal, and gastrointestinal) | Haemodynamic variables
Number of associated
complications on admission
ADL, ABG
APACHE II, and age |
| Scala et al. (Intensive Care Medicine 2004) [9] | Respiratory monitoring unit in a respiratory ward | 72 | NIMV (100% of pts at admission)
IMV (6% of NIMV failed pts) | 7.28
78
183 | (III) 61 | 40 (acute comorbidities)
20 (chronic comorbidities) | Acute and chronic comorbidities.
Cardiovascular and noncardiovascular ones | Acute cardiovascular comorbidities (influence on NIMV failure) Acute comorbidities and chronic noncardiovascular ones (influence on 6-month mortality) |
|
Nevins and Epstein (Chest 2001) [20] | ICUs | 67 | IMV (100% of pts) | 7.27
68
92 | (II) 13 | 42 | Chronic comorbidities and those included in APACHE II | Need of mechanical ventilation
APACHE II
More than 1 comorbidity |
Seneff et al.
(JAMA 1995) [10] | ICUs | 66 | IMV (47% of COPD patients) | — | (III) 57 | — | Chronic comorbidities included in APACHE III. Respiratory and nonrespiratory | APACHE III
Length of stay before ICU admission |
|
