Research Article

Analgesic, Anti-Inflammatory, and Chondroprotective Activities of Cryptolepis buchanani Extract: In Vitro and In Vivo Studies

Table 1

Effects of CBE and indomethacin on acetic acid-induced writhing response in mice (n = 6).

TreatmentNumber of writhes% inhibition

80% Tween32.00 ± 2.71
CBE 60 mg/kg22.00 ± 1.36*,††31.25
CBE 125 mg/kg16.00 ± 0.96*,†50.00
CBE 250 mg/kg15.83 ± 1.25*,†50.53
Indomethacin 5 mg/kg9.50 ± 0.96*70.31

Results are mean of number of writhes ± S.E.M. *P ≤ 0.001 compared with control group. P 0.01 and ††P 0.001 compared with indomethacin group.