Analgesic, Anti-Inflammatory, and Chondroprotective Activities of Cryptolepis buchanani Extract: In Vitro and In Vivo Studies

Table 2

Effects of CBE and indomethacin on EPP-induced ear edema in rats (n = 10).

Treatment	Edema thickness (mm)
	15 min	30 min	60 min	120 min
5% DMSO in ethanol/ear	89 ± 3.79	163 ± 5.98	240 ± 8.70	169 ± 16.17
CBE 1 mg/ear	35 ± 6.20*	64 ± 4.99*	90 ± 9.55*	63 ± 10.23*
Indomethacin 1 mg/ear	20 ± 5.78*	53 ± 11.37*	96 ± 12.68*	65 ± 4.28*

Results are mean of edema thickness ± S.E.M. *P 0.001 compared with control group.