Low Dose of Valproate Improves Motor Function after Traumatic Brain Injury

Figure 5

Postinjury administration of 30 mg/kg/day VPA for 7 days reduces GFAP expression. Strong immunostaining of GFAP was demonstrated 7 days after TBI, but these activations were significantly attenuated in the VPA-treated group. (Data are presented as the mean ± SEM, significant difference by 1-way ANOVA followed by Dunnett’s post hoc test. ^†𝑃=.005, 𝑛=3 per group.)