Clinical Study of Nasopharyngeal Carcinoma Treated by Helical Tomotherapy in China: 5-Year Outcomes

Table 7

Outcomes of IMRT for NPC in published series.

Author (year)	Number of patients	Treatment period	Median follow-up (m)	Stage	Treatment arms	Time point (y)	LC (LRFS)	RC (NRFS)	DMFS	OS
Tham et al. (2009) [6]	195	2002–2005	37	I–IVB	RT or CRT	3	93%	NR	89%	94%
Lee et al. (2009) [5]	68	2003–2005	30	I–IVB	RT or CRT	2	93%	91%	85%	80%
Su et al. (2012) [9]	198	2001–2008	51	I–IIB	RT	5	98%	NR	98%	97%*
Lai et al. (2011) [10]	512	2003–2006	53	I–IVB	RT or CRT	5	93%	97%	84%	NR
Lin et al. (2010) [7]	370	2003–2007	31	IIB–IVB	RT or CRT	3	95%	97%	81%	89%
Ng et al. (2011) [8]	193	2005–2007	30	I–IVB	RT or CRT	2	95%	96%	90%	92%
Peng et al. (2012) [11]	306	2003–2008	42	I–IVB	RT or CRT	5	90.5%	91.7%	NR	79.6%
Wang et al. (2012) [29]	138	2006–2009	23	I–IVB	RT or CRT	3	94%	96%	80%	83%
This study	190	2007–2012	32	I–IVB	RT or CRT or ART	3	96%	98%	92%	86%

RT: radiation therapy alone; CRT: chemoradiotherapy; ART: radiation therapy concurrent with anti-EGFR Mab therapy; LC: local control; LRFS: local relapse-free survival; RC: regional control; NRFS: nodal relapse-free survival; DMFS: distant metastases-free survival; OS: overall survival; NR: not reported; *disease-specific survival.