Inhibition of Ceramide <i>De Novo</i> Synthesis with  Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes

<table>Effect of myriocin treatment (for 7 days) and streptozotocin-induced diabetes (for 7 days) on sphingomyelin (a), sphingosine (b), and sphingosine-1-phosphate (c) contents in liver homogenates. C: control group. M: group treated with myriocin. D: streptozotocin-induced diabetes group. D + M: treptozotocin-induced group treated with myriocin. Results are based on 8 independent preparations for each experimental treatment (means ± SE). *<svg height="11.375" id="M46" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with C group. <sup>†</sup><svg height="11.375" id="M47" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with D group.</table>

BioMed Research International

fig2

Figure 2

Figure 2: Inhibition of Ceramide <i>De Novo</i> Synthesis with  Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes 

Figure 2 | Inhibition of Ceramide De Novo Synthesis with  Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes 