Inhibition of Ceramide <i>De Novo</i> Synthesis with  Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes

<table>Effect of myriocin treatment (for 7 days) and streptozotocin-induced diabetes (for 7 days) on neutral ceramidase (a) and alkaline ceramidase (b) activities in liver homogenates. C: control group. M: group treated with myriocin. D: streptozotocin-induced diabetes group. D + M: streptozotocin-induced group treated with myriocin. Results are based on 8 independent preparations for each experimental treatment (means ± SE). *<svg height="11.375" id="M55" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with C group. <sup>†</sup><svg height="11.375" id="M56" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with D group.</table>

BioMed Research International

fig4

Figure 4

Figure 4: Inhibition of Ceramide <i>De Novo</i> Synthesis with  Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes 

Figure 4 | Inhibition of Ceramide De Novo Synthesis with  Myriocin Affects Lipid Metabolism in the Liver of Rats with Streptozotocin-Induced Type 1 Diabetes 