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BioMed Research International
Volume 2014, Article ID 981261, 7 pages
http://dx.doi.org/10.1155/2014/981261
Research Article

Stem Cell-Like Circulating Tumor Cells Indicate Poor Prognosis in Gastric Cancer

1Department of Digestive, The Second Hospital of Tianjin Medical University, Tianjin 300211, China
2Tianjin Children Hospital, Tianjin 300074, China

Received 22 April 2014; Revised 11 May 2014; Accepted 12 May 2014; Published 22 May 2014

Academic Editor: Shiwu Zhang

Copyright © 2014 Man Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. E. Han, Y. S. Lee, S. Y. Baek, B. S. Kim, J. B. Kim, and S. O. Oh, “Hedgehog signaling regulates the survival of gastric cancer cells by regulating the expression of Bcl-2,” International Journal of Molecular Sciences, vol. 10, no. 7, pp. 3033–3043, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Correia, J. C. Machado, and A. Ristimaki, “Basic aspects of gastric cancer,” Helicobacter, vol. 14, supplement 1, pp. 36–40, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. I. Baccelli, A. Schneeweiss, S. Riethdorf et al., “Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay,” Nature Biotechnology, vol. 31, no. 6, pp. 539–544, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. S. J. Cohen, C. J. Punt, N. Iannotti et al., “Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer,” Journal of Clinical Oncology, vol. 26, no. 19, pp. 3213–3221, 2008. View at Publisher · View at Google Scholar
  5. I. Tinhofer, M. Saki, F. Niehr, and V. Budach, “Cancer stem cell characteristics of circulating tumor cells,” International Journal of Radiation Biology, 2014. View at Publisher · View at Google Scholar
  6. B. Illert, M. Fein, C. Otto et al., “Disseminated tumor cells in the blood of patients with gastric cancer are an independent predictive marker of poor prognosis,” Scandinavian Journal of Gastroenterology, vol. 40, no. 7, pp. 843–849, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Takaishi, T. Okumura, S. Tu et al., “Identification of gastric cancer stem cells using the cell surface marker CD44,” Stem Cells, vol. 27, no. 5, pp. 1006–1020, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Meng, D. Tripathy, E. P. Frenkel et al., “Circulating tumor cells in patients with breast cancer dormancy,” Clinical Cancer Research, vol. 10, no. 24, pp. 8152–8162, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. Z. F. Jiang, M. Cristofanilli, Z. M. Shao et al., “Circulating tumor cells predict progression-free and overall survival in Chinese patients with metastatic breast cancer, HER2-positive or triple-negative (CBCSG004): a multicenter, double-blind, prospective trial,” Annals of Oncology, vol. 24, no. 11, pp. 2766–2772, 2013. View at Publisher · View at Google Scholar
  10. T. J. Hiltermann, M. M. Pore, A. van den Berg et al., “Circulating tumor cells in small-cell lung cancer: a predictive and prognostic factor,” Annals of Oncology, vol. 23, no. 11, pp. 2937–2942, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Alix-Panabieres and K. Pantel, “Circulating tumor cells: liquid biopsy of cancer,” Clinical Chemistry, vol. 59, no. 1, pp. 110–118, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. G. Lurje, M. Schiesser, A. Claudius, and P. M. Schneider, “Circulating tumor cells in gastrointestinal malignancies: current techniques and clinical implications,” Journal of Oncology, vol. 2010, Article ID 392652, 9 pages, 2010. View at Publisher · View at Google Scholar
  13. C. Alix-Panabieres and K. Pantel, “Technologies for detection of circulating tumor cells: facts and vision,” Lab on a Chip, vol. 14, no. 1, pp. 57–62, 2014. View at Publisher · View at Google Scholar
  14. Y. Zhang, J. Li, L. Cao, W. Xu, and Z. Yin, “Circulating tumor cells in hepatocellular carcinoma: detection techniques, clinical implications, and future perspectives,” Seminars in Oncology, vol. 39, no. 4, pp. 449–460, 2012. View at Publisher · View at Google Scholar · View at Scopus
  15. A. A. Saad, N. M. Awed, N. N. A. Abd Elkerim et al., “Prognostic significance of E-cadherin expression and peripheral blood micrometastasis in gastric carcinoma patients,” Annals of Surgical Oncology, vol. 17, no. 11, pp. 3059–3067, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. S. M. Yie, B. Lou, S. Ye et al., “Detection of survivin-expressing circulating cancer cells (CCCs) in peripheral blood of patients with gastric and colorectal cancer reveals high risks of relapse,” Annals of Surgical Oncology, vol. 15, no. 11, pp. 3073–3082, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. T. Koga, E. Tokunaga, Y. Sumiyoshi et al., “Detection of circulating gastric cancer cells in peripheral blood using real time quantitative RT-PCR,” Hepato-Gastroenterology, vol. 55, no. 84, pp. 1131–1135, 2008. View at Google Scholar · View at Scopus
  18. N. Wang, L. Shi, H. Li et al., “Detection of circulating tumor cells and tumor stem cells in patients with breast cancer by using flow cytometry,” Tumor Biology, vol. 33, no. 2, pp. 561–569, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. P. A. Theodoropoulos, H. Polioudaki, S. Agelaki et al., “Circulating tumor cells with a putative stem cell phenotype in peripheral blood of patients with breast cancer,” Cancer Letters, vol. 288, no. 1, pp. 99–106, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. F. Sun, Y. Xu, X. R. Yang et al., “Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection,” Hepatology, vol. 57, no. 4, pp. 1458–1468, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. C. Zhang, C. Li, F. He, Y. Cai, and H. Yang, “Identification of CD44+CD24+ gastric cancer stem cells,” Journal of Cancer Research and Clinical Oncology, vol. 137, no. 11, pp. 1679–1686, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Matsusaka, K. Chìn, M. Ogura et al., “Circulating tumor cells as a surrogate marker for determining response to chemotherapy in patients with advanced gastric cancer,” Cancer Science, vol. 101, no. 4, pp. 1067–1071, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Cristofanilli, G. T. Budd, M. J. Ellis et al., “Circulating tumor cells, disease progression, and survival in metastatic breast cancer,” The New England Journal of Medicine, vol. 351, no. 8, pp. 781–791, 2004. View at Publisher · View at Google Scholar · View at Scopus