Research Article
Alkylation of Histidine Residues of Bothrops jararacussu Venom Proteins and Isolated Phospholipases : A Biotechnological Tool to Improve the Production of Antibodies
Table 2
Neutralization of edema, PLA2 activity, and 2x LD50 induced by the respective antibodies of native and modified forms of B. jararacussu crude venom and isolated toxins.
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LD50 assay was done after previous incubation of the venom or toxin with its respective antibody (1 : 50, w/w) for 30 min at 37°C. Results express the percentage of animal survival. |