Arrabidaea chica Hexanic Extract Induces Mitochondrion Damage and Peptidase Inhibition on Leishmania spp.
Figure 3
Anti-intracellular amastigote activity of the B2 fraction from the A. chica hexanic extract. B2-treated macrophages previously infected with Leishmania were incubated in fresh medium at 28°C for 72 hours. The number of promastigote forms obtained from macrophages cultures was counted using a hemocytometer chamber. Each point represents the mean ± S.E. of 2 independent experiments performed in triplicate. MIC and subMIC values for L. amazonensis and L. infantum were 37.2 and 18.6 μg/mL and 18.6 and 9.3 μg/mL, respectively. Asterisks indicate that treated parasites were statistically different () from control parasites.
