Modulation of Wolframin Expression in Human Placenta during
Pregnancy: Comparison among Physiological and Pathological States
Figure 1
(a) Very high wolframin expression distributed in the cytotrophoblast cells of placental villi from the first trimester voluntary termination of gestation (VTG), 150x; (b) higher magnification showing the very high immunostaining for wolframin localized at perinuclear level in the cytotrophoblast cells from VTG, 640x; (c) moderate wolframin expression in the cytotrophoblast cells and in the stroma of placental villi from loss of pregnancy (LP), 150x; (d) higher magnification showing the moderate wolframin immunopositivity in the cytoplasm of cytotrophoblast cells from LP, 640x; (e) representative negative control of the first trimester VTG, 150x; (f) representative negative control of the third trimester vaginal delivery (VD), 150x. For all the images, C represents cytotrophoblast and S represents syncytiotrophoblast.
