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BioMed Research International
Volume 2014 (2014), Article ID 986352, 6 pages
Review Article

Ablative Therapies for Colorectal Polyps and Malignancy

Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263, USA

Received 28 February 2014; Revised 23 May 2014; Accepted 9 June 2014; Published 26 June 2014

Academic Editor: Boris Kuvshinoff

Copyright © 2014 Jacqueline Oxenberg et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Endoscopic techniques are gaining popularity in the management of colorectal polyps and occasionally superficial cancers. While their use is in many times palliative, they have proven to be curative in carefully selected patients with polyps or malignancies, with less morbidity than radical resection. However, one should note that data supporting local and ablative therapies for colorectal cancer is scarce and may be subject to publication bias. Therefore, for curative intent, these techniques should only be considered in highly select cases as higher rates of local recurrences have also been reported. The aim of this review is to explain the different modalities of local and ablative therapies specific to colorectal neoplasia and explain the indications and circumstances where they have been most successful.