Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future

Figure 5

Western-blot analysis showing the PARP cleavage in BCBL1 cells treated for 24 hours with all the above reported cytotoxic drugs: LY294002 (LY), SB203580 (SB), SP600125 (SP), PD98059 (PD), AG490 (AG), PES, and Benzisoxazole (BENZ). β-Actin is included as loading control and a representative experiment out of three is reported. Antibodies against PARP (Cell Signaling) and β-actin (Sigma Aldrich) were diluted 1 : 1000 and 1 : 10000, respectively.