Review Article

Update on the Pathogenic Implications and Clinical Potential of microRNAs in Cardiac Disease

Figure 5

microRNA network in cardiac physiology and pathologies. The expression of miRNAs found of relevant importance in cardiac development (boxed miRNAs) is also involved in the remodeling process of the heart. Different modulation of miRNA expression enhances pathological outcomes at the myocardium and can be specifically targeted in a precise manner to improve the therapeutic applicability of miRNAs.