A Novel Mouse Model of Peritoneal Dialysis: Combination of Uraemia and Long-Term Exposure to PD Fluid

Figure 3

(a and b) Blood chemistries at days 0 and 70, respectively, before and after induction of uraemia with 5/6 nephrectomy. (a) Serum levels of creatinine. Time 0: 5/6 NX versus control; time 70: 5/6 NX versus control. (b) Serum levels of urea: white bars indicate healthy controls; black bars indicate mice undergoing 5/6 nephrectomy. values < 0.01, < 0.001. (c) Mean increases in body weight during uraemia induction. Values are expressed as percent of starting body weight. Black line indicates healthy controls, blue line indicates uremic group, and red line indicates uremic group undergoing PD.

(a) Serum creatinine

(b) Serum urea

(c) Body weight