A Novel Mouse Model of Peritoneal Dialysis: Combination of Uraemia and Long-Term Exposure to PD Fluid

Figure 4

Effect of uraemia and PD fluid exposure on the parietal peritoneal thickness. (a–d) Masson’s trichrome staining of parietal peritoneum showed a slight and a high increase of extracellular matrix deposition in mice undergoing 5/6 nephrectomy, respectively, exposed (c) or not (b) to standard PD fluid. Magnification ×20. (Control: ; 5/6 NX: ; 5/6 NX + PD: .) values < 0.001.

(a) Control

(b) 5/6 NX

(c) Dianeal (5/6 NX)

(d) Thickness