Application of Molecular Modeling to Development of New Factor Xa Inhibitors

Figure 2

Enrichment curve for docked ligands of factor Xa. AUC = 0.94. We denote the total number of the ligands ranged by scoring function as (total), the total number of the active compounds as (total active), the top ligands from this ranged list of the ligands as , and the number of active ligands from these top ligands as (active). Then (total) and (active)/ (total active).