Application of Molecular Modeling to Development of New Factor Xa Inhibitors

Table 1

The docking and postdocking optimization results for the factor Xa test set of ligands.

After SOL	After DISCORE
3 false-positive ligands	0 false-positive ligands
1 false-negative ligand	0 false-negative ligands
23 true-negative ligands	26 true-negative ligands
37 true-positive ligands	38 true-positive ligands