Application of Molecular Modeling to Development of New Factor Xa Inhibitors

Table 4

ID, structure, SOL scoring function, and results of experimental measurements of factor Xa activity in the presence of 17f compound.

ID	Structure	SOL score, kcal/mol	DISCORE score, kcal/mol	Activity of factor Xa in the presence of the inhibitor, IC50, mcM
17f		−7,05	−3,04	0,7