Gene Signature of Human Oral Mucosa Fibroblasts: Comparison with Dermal Fibroblasts and Induced Pluripotent Stem Cells

Figure 1

Gene expression signatures in hOFs, hDFs, and hOF-iPSCs. (a) Heat map and hierarchical clustering of whole microarray probes for each of the nine samples. Three individual samples were prepared from each of three types of cells, hOFs, hDFs, and hOF-iPSCs. (b) Comparisons of average signal values among the three types of cells, hOFs, hDFs, and hOF-iPSCs. The number indicates differentially expressed genes (, ≥2-fold change; upper panel, left). Scatter plots comparing the average signal values of three samples are shown and the number of differentially expressed probes at more than 2-fold levels is indicated as follows: hOFs versus hDFs (upper panel, right), hOFs versus hOF-iPSCs (lower panel, left), and hDFs versus hOF-iPSCs (lower panel, right).

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