Gene Knockout Identification Using an Extension of Bees Hill Flux Balance Analysis

Table 7

Comparison between average computational time of BHFBA and BAFBA for 1000 iterations.

Model	Method	Computation time (seconds)
E. coli	BHFBA	3223
	BAFBA [9]	10253
	OptKnock [3]	N/A
	SA + FBA [5]	N/A
B. subtilis	BHFBA	7028
	BAFBA [9]	22515
	OptKnock [3]	N/A
	SA + FBA [5]	N/A
C. thermocellum	BHFBA	2880
	BAFBA [9]	10282
	OptKnock [3]	N/A
	SA + FBA [5]	N/A

Note. The bold numbers represent the best result. N/A represents that the results are not reported in literature.