Clinical Study

Effects of High Volume Haemodiafiltration on Inflammatory Response Profile and Microcirculation in Patients with Septic Shock

Table 2

Effects of HVHDF on haemodynamic and clinical variables.

Before HVHDFAfter HVHDF

Mean arterial pressure (mmHg)89 (71–91)80 (73–93)NS
Cardiac index (L/min per m2)3.02 (2.5–4.2)2.9 (2.5–3.3)NS
Heart rate (beats/min)102.4 (26.8)98.5 (22.9)NS
Body temperature (°C)37.1 (0.6)36.9 (0.6)NS
Arterial pH7.36 (0.07)7.40 (0.06)0.013
Norepinephrine dose (μg/kg/min)0.40 (0.43)0.28 (0.33)0.009
Lactate (mmol/L)1.5 (1.2–3.0)1.5 (1.2–2.1)NS
SOFA10 (7–11)9 (7–12)NS

HVHDF: high volume haemodiafiltration; SOFA: sequential organ failure score. Data presented as mean (standard deviation) or median (interquartile range).