Biochemical and Functional Comparisons of mdx and Sgcg^−/− Muscular Dystrophy Mouse Models

Figure 2

Consistent with severe pathology the Sgcg^−/− D2 mice weighed less that their wild type D2 controls throughout the 16 weeks. Wild type D2 mice weighed significantly more than the Sgcg^−/− D2 mice at 4 and 12 weeks. significance by Student’s t-test versus Sgcg^−/− D2 animals. –20.