The Influence of Metabolic Factors for Nonalcoholic Fatty Liver Disease in Women
Table 3
Comparison of baseline characteristics in premenopausal women without NAFLD versus with NAFLD.
Premenopausal women without NAFLD
Premenopausal women with NAFLD
P
Number of subjects
623
105
Age, years
46.3 ± 8.0
50.8 ± 9.0
<0.001
Body mass index, kg/m2
21.1 ± 2.3
24.6 ± 3.3
<0.001
Waist circumference, cm
77.5 ± 6.2
85.6 ± 7.2
<0.001
AST, IU/L
19.1 ± 5.9
22.7 ± 9.7
<0.001
ALT, IU/L
19.3 ± 8.9
28.3 ± 17.0
<0.001
GGT, IU/L
18.0 ± 13.3
27.3 ± 19.4
<0.001
Fasting glucose, mg/dL
89.1 ± 8.5
98.9 ± 17.0
<0.001
Triglycerides, mg/dL
75.5 ± 39.6
137.2 ± 97.8
<0.001
HDL-cholesterol, mg/dL
61.7 ± 12.3
52.0 ± 10.1
<0.001
LDL-cholesterol, mg/dL
115.7 ± 26.9
129.6 ± 30.7
<0.001
CRP, mg/dL
0.07 ± 0.2
0.13 ± 0.1
0.012
HOMA
1.2 ± 0.6
2.5 ± 1.8
<0.001
Smoking, %
2.9
1.9
0.742
Regular exercise, %
34.2
46.7
0.103
Hypertension, %
14.0
35.2
<0.001
Diabetes, %
8.5
33.3
<0.001
Metabolic syndrome, %
5.5
28.6
<0.001
Data are presented as the mean ± SD. P value by Student’s t-test for continuous variables and chi-square test for categorical variables. ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transpeptidase; HDL: high density lipoprotein; LDL: low density lipoprotein; CRP: C-reactive protein; HOMA: homeostasis model assessment-estimated insulin resistance; NAFLD: nonalcoholic fatty liver disease.
