The Influence of Metabolic Factors for Nonalcoholic Fatty Liver Disease in Women

Table 4

Unadjusted and adjusted analyses for the risk of NAFLD in all subjects.

	Unadjusted OR (95% CI)	P	Adjusted OR (95% CI)	P
Age	1.05 (1.03–1.07)	<0.001	1.00 (0.97–1.03)	0.989
Postmenopause	2.02 (1.42–2.86)	<0.001	1.07 (0.64–1.79)	0.803
Hypertension	2.97 (2.09–4.21)	<0.001	1.52 (0.96–2.38)	0.073
Diabetes	4.52 (3.08–6.64)	<0.001	2.35 (1.40–3.95)	0.001
Triglyceridemia	6.47 (4.12–10.18)	<0.001	3.22 (1.81–5.72)	<0.001
HDL	0.33 (0.23–0.48)	<0.001	0.60 (0.38–0.97)	0.036
Central obesity	6.45 (4.48–9.27)	<0.001	3.67 (2.36–5.70)	<0.001
Smoking	0.93 (0.34–2.53)	0.891	0.75 (0.23–2.46)	0.628
Exercise	1.43 (1.00–2.05)	0.052	1.56 (0.99–2.47)	0.057
ALT	1.08 (1.06–1.10)	<0.001	1.07 (1.04–1.09)	<0.001
GGT	1.02 (1.01–1.03)	<0.001	1.00 (0.99–1.01)	0.353
HOMA	2.33 (1.91–2.54)	<0.001	1.23 (0.97–1.56)	0.093

NAFLD: nonalcoholic fatty liver disease; ALT: alanine aminotransferase; GGT: gamma-glutamyl transpeptidase; OR: odds ratio; CI: confidence interval; HDL: high density lipoprotein; HOMA: homeostasis model assessment-estimated insulin resistance.