Therapeutic Efficacy of E-64-d, a Selective Calpain Inhibitor, in Experimental Acute Spinal Cord Injury

Figure 3

(a) Representative images of NeuN and TUNEL-stained sections of rats treated with different drugs for 3 d. (b) Quantification of NeuN and TUNEL double positive cells. (c) Activity of caspase-3 in injured spinal cord from each group. (d) Protein expressions of AIF and MAP1B analyzed by Western blotting. (e) The relative densities of AIF and MAP1B (β-actin and VADC served as internal references). , E-64-d treatment versus E-64-d + MP treatment; , compared with SCI group.

(a)

(b)

(c)

(d)

(e)