Research Article

Comparative Study of the Accuracy of Different Techniques for the Laboratory Diagnosis of Schistosomiasis Mansoni in Areas of Low Endemicity in Barra Mansa City, Rio de Janeiro State, Brazil

Table 6

Concordance between the positive results obtained using the COPT technique and those obtained using the other techniques, in fecal and serum samples collected from the sample population in the city of Barra Mansa, RJ, 2011.

TechniquesCOPTTotalIC (95%)
NegativePositive McNemarKappa
(%) (%) (%)LowerHigher

KK-HH
 Negative542 (94.8)25 (4.4)567 (99.1)<0.0010.2240.0380.409
 Positive1 (0.2)4 (0.7)5 (0.9)
 Total543 (94.9)29 (5.1)572 (100.0)
ELISA-IgG
 Negative530 (86.6)11 (1.8)541 (88.4)<0.0010.3770.2550.500
 Positive49 (8.0)22 (3.6)71 (11.6)
 Total579 (94.6)33 (5.4)612 (100.0)
ELISA-IgM
 Negative475 (77.6)6 (1)481 (78.6)<0.0010.2660.1780.354
 Positive104 (17.0)27 (4.4)131 (21.4)
 Total579 (94.6)33 (5.4)612 (100.0)
IFT-IgM
 Negative508 (83.0)7 (1.1)515 (84.2)<0.0010.3470.2410.454
 Positive71 (11.6)26 (4.2)97 (15.8)
 Total579 (94.6)33 (5.4)612 (100.0)
qPCR-feces
 Negative503 (87.9)14 (2.4)517 (90.4)0.0010.3110.1760.446
 Positive40 (7.0)15 (2.6)55 (9.6)
 Total543 (94.9)29 (5.1)572 (100.0)
qPCR-serum
 Negative574 (93.8)29 (4.7)603 (98.5)<0.0010.1710.0130.330
 Positive5 (0.8)4 (0.7)9 (1.5)
 Total579 (94.6)33 (5.4)612 (100.0)